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Alterations in global mRNA decay broadly impact multiple stages of gene expression, although signals that connect these processes are incompletely defined.
The mechanisms underlying these processes are incompletely understood.
A final point on the UPS is that misfolded proteins are subjected to a higher rate of degradation than are normal proteins, but these recognition processes are incompletely understood.
More recently, it has become appreciated that Caspase-2 has non-apoptotic roles in cell cycle arrest, genome stability and tumor suppression, yet the mechanisms behind these processes are incompletely understood.
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Although the biochemical mechanisms underlying this process are incompletely defined, there is compelling evidence that SDF-1/CXCL12 stimulation of CXCR4 is a principal regulator for retention and stress-induced mobilization of myeloid lineage cells from the bone marrow to the blood [16] [18].
AA is characterized by degradation of ECM, but the mechanisms underlying this process are incompletely understood.
The roles of paracrine signals from BM-MSCs in this process are incompletely understood.
However, even in RAGE null mice, the activation of the inflammatory process is incompletely inhibited suggesting that AGE/RAGE may be an incomplete part of the mechanism for the development of neuropathy.
Centrosomes also duplicate during cell division, but the mechanism controlling this process is incompletely understood.
Inflammation plays an important role in the pathogenesis of bronchopulmonary dysplasia (BPD), but the exact nature of this inflammatory process is incompletely understood.
However, this process is incompletely understood.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com