Dr. MacPherson likened the process to proofreading the listings in a phone book.
The strain of proofreading his almost illegible handwriting helped ruin her eyesight, too.
Let this be a lesson in the importance of proofreading.
"We have only one printing machine here and we have been running it non-stop to make sure that these books are done," says Sister Catherine as she explains how her small team of four volunteers has worked through the cumbersome process of translating, embossing, printing, proofreading and then binding the books.
The 1-bp backtracked state is closely associated with the proofreading process of Pol II, as the enzyme in this location preferentially cleaves the 3′ dinucleotide of the RNA containing the mismatched base, empting the active site for NTP binding (Wang et al., 2009).
We thank Helen Glanville of for proofreading the manuscript and improving the language.
Mutations leading to drug resistance are generated frequently, since the process of reverse transcription lacks a proofreading mechanism and generates single nucleotide mutations at a high rate (3.4 * 10−5 per nucleotide base per cycle of replication; [1]).
The assignment familiarized students with the vocabulary, major enzymatic players, and processes of DNA polymerase proofreading and mismatch repair.
As the process of reverse transcription is highly error-prone due to the lack of proofreading, the daughter copies can differ from the master copy [ 13].
State officials conceded that four other mistakes indicated a certain sloppiness or lack of proofreading.
Due to the lack of proofreading in RNA-dependent RNA polymerases, RNA viruses have extraordinarily high rates of mutation.
