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Neurovascular dysfunction is a central process in the pathogenesis of stroke and most neurodegenerative diseases, including Alzheimer's disease.
Apparently, PM014 induced up-regulation of epithelial markers and down-regulation of mesenchymal markers in vivo and in vitro, suggesting that PM014 may target EMT process in the pathogenesis of pulmonary fibrosis.
Elastic fiber injury is an important process in the pathogenesis of chronic obstructive pulmonary disease (COPD), particularly with regard to the development of pulmonary emphysema.
Dysfunctional accumulation of amyloid-β (Aβ) protein stimulated by Cu2+ is considered as a key process in the pathogenesis of Alzheimer's disease (AD).
This could be an early and crucial process in the pathogenesis of FALS.
Inflammation is a key process in the pathogenesis of atherosclerosis (AS).
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Such information could further clarify early microvascular processes in the pathogenesis of kidney disease.
The present review summarized the previous studies which discussed the role of autophagic processes in the pathogenesis of inflammation, including elimination of pathogens, regulation of innate or adaptive immune response.
Among other implications, these findings are further evidence for a role of adaptive immune processes in the pathogenesis of IPF [3] [15], [17].
Foxo1 controls two important processes in the pathogenesis of type 2 diabetes: hepatic glucose production and β-cell compensation of insulin resistance [24].
The main processes in the pathogenesis of cerebral malaria caused by Plasmodium falciparum involved sequestration of parasitized red blood cells and immunopathological responses.
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