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The experimental process for validation purposes consisted of monitoring metallic sheets within a range of 0 35% (perforation rates), black-white (colors) and galvanized steel-aluminum (materials) in a large-scale test campaign.
Then, a detailed model is developed within the buildingEXODUS environment, which is assumed as a reliable representation of the evacuation process for validation and tuning of the SimEvents model, making up for the lack of suitable experimental data.
Finally, we demonstrate how this modelling approach can be integrated in the network definition process for validation purposes.
Among current investigations, the Foundation of NIH OA Biomarkers Consortium has established and initiated a process for validation and qualification of the most promising commercially available biomarkers in OA [ 5].
The research process for validation of indicators involves collecting empirical data through direct observations of care in a facility and directly comparing this data with both health worker reports and maternal recall of events.
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Qualitative data were analysed using constant comparison and processes for validation.
A phosphoribulokinase was chosen as a representative for photosynthesis-related processes for validation of RNA-Seq data.
Especially when many different samples have to be processed for validation of biomarker candidates, handling many microarrays is much easier and also for screening approaches microarrays are best suited and will replace membrane-based macroarray screens.
The process developed for validation and improvement of the structural annotation can be applied on a genome scale to support experimental studies of the molecular events associated with mycorrhizal symbiosis as well as facilitate better comparative genomics and evolutionary analyses of gene families and their functions.
To facilitate improvements in biomarker translation medicine Pepe et al. proposed a systematic process for biomarker validation for early detection of cancer with 5 distinct phases, each phase providing increased level of evidence of marker validation [20].
However, the process for their validation is slow and messy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com