At this stage, it is not known how efficiently SVSPs are processed for presentation through the MHC class I pathway.
To verify that antigens are initially sequestered in DALIS RAW309 macrophages were infected with a recombinant adenovirus expressing ovalbumin (Ad-OVA), which is processed for presentation on MHC class I molecules in this situation.
Images were processed for presentation using MetaMorph and ImageJ.
All images were digitally processed for presentation with Adobe Photoshop.
On the other hand, tumour mRNA expressed in DCs would be processed for presentation by HLA class I molecules.
Images were analyzed and processed for presentation using brightness and contrast adjustment with ImageJ software (NIH Software, Bethesda, MD).
Antigens are subsequently processed for presentation on Major Histocompatibility Complex (MHC) molecules as well as (in the case of the Mycobacterium tuberculosis lipoarabinomannan component [ 12]) on CD1b.
In doing so, BCG may limit the range of antigens that are processed for presentation by major histocompatibility complex (MHC) class II.
However, Ags internalised through these C-type lectins can also be processed for presentation to T cells 7. Targeting lectins on DCs has been increasingly used in preclinical models for the in vivo targeting of Ags to these cells 8.
Exposure in infectious disease also can refer to events after a foreign antigen is internalized and processed for presentation to the immune system, often measured serologically (e.g., through antibodies).
