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Briefly, a term in the Biological Process branch of the Gene Ontology was considered specific if it was associated with fewer than 30 yeast genes, and two genes were considered to have a specific functional relationship if they shared any of those specific terms [14].
Gene annotations were limited to 'biological process' branch of the ontology and downloaded from the Mouse Genome Informatics (MGI) database.
The Affymetrix HG-U133A microarray contains 10937 genes annotated within the biological process branch of the Gene Ontology (GO) (Ashburner et al, 2000).
Significantly enriched functional categories of genes, annotated with terms from the Biological Process branch of the Gene Ontology, are presented in Table 3.
This curation was performed for all GO terms from the biological process branch of the ontology without information of their hierarchical relationships, and each set of resulting responses was corrected for hierarchical inconsistencies.
Only GO terms from the biological process branch of the Gene Ontology were used since we would expect similarities in GO terms from this branch to be better reflected in expression profile similarities than other branches (e.g. Molecular Function).
Similar(53)
As stated by McKay [23], the check for canonical augmentation is branchindependent, which would allow to process branches of the generation trees in parallel.
The National Institute on Aging and the Administration on Aging are now financing caregiving studies on "things that just kind of make the life of an Alzheimer's patient and his or her caregiver less burdensome," said Sidney M. Stahl, chief of the Individual Behavioral Processes branch of the Institute on Aging.
"We're used to looking at groups and complaining that their mortality rates haven't improved fast enough, but to actually go backward is deeply troubling," said John G. Haaga, head of the Population and Social Processes Branch of the National Institute on Aging, who was not involved in the new study.
"We're used to looking at groups and complaining that their mortality rates haven't improved fast enough, but to actually go backward is deeply troubling," John G. Haaga, head of the Population and Social Processes Branch of the National Institute on Aging, who was not involved in the new study, told The New York Times.
From the 'Biological processes' branch of the Gene Ontology, the gene set 'Other carbon metabolism' was significantly enriched in B10.Q.
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