The algorithm proceeds in successive rounds of genetic modifications and selection of a collection of independent GTRNs (typically 10 "cells" or simulations), a general strategy in evolutionary computation.
Following completion of anaphase, CCNB is degraded, thus returning the cell to G1 state, which, in the presence of stimulation by growth factors, proceeds by successive cycles of cell division.
The presented mechanistic approach is embedded in the classical framework of a multistage and evolutionary cancer model where individual somatic cancer evolution starts with one cell and proceeds with successive rounds of mutation acquisitions, clonal expansions and partial elimination of tumor subclones by various mechanisms (Beckman and Loeb, 2005a).
Polymerization of styrene (CH2=CHC6H5) with sulfuric acid (H2SO4) typifies this process: Polymerization then proceeds by successive additions of the cationic chain end to monomer molecules.
The development of the kidney proceeds through a series of successive phases, which include pronephros, mesonephros, and metanephros that develop in a cranio-caudal fashion [ 3, 4].
It was found, irrespective of the applied parameters, that the deposition proceeds through successive nucleation and growth steps.
In aprotic media electrochemical reduction of these compounds proceeds in two successive steps; the first of them leads to formation of a stable anion-radical, the second one leads to the formation of an unstable primary product.
Calculations must proceed by a process of successive approximations, during which the flux of energy is taken to be constant with depth.
Epidermal differentiation proceeds through successive steps that lead proliferative keratinocytes, positive for cytokeratins K5 and K14, to undergo terminal differentiation with the appearance of specific markers like K1, K10 and involucrin.
Thus, in the determination of heme oxygenase activity in vitro, it is important to ensure that the reaction proceeds through successive oxygenation steps.
Cells with advantageous mutations eventually outgrow competing cells and tumor development proceeds by successive clonal expansions.
