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If situations have minimal or skeptical business input, then proceed with alignment anyway, and seek out confirmation in subsequent phases of EIM.
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One possible solution would be to correct the PET dataset with an edge-preserving prior first, then align it to the anatomical information image of choice and, once a correct alignment is achieved, proceed with a new reconstruction of the PET dataset with the help of anatomical information.
Extensions then proceed with the next AFP that meets given distance criteria restricting the alignment to low gap sizes.
Still, proceed with caution.
So proceed with caution.
And finally, proceed with humility.
We must proceed with caution".
Yellow, proceed with caution.
Amber usually means proceed with caution.
Lots of spoilers, so proceed with caution.
You have to proceed with caution".
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