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To evaluate the predictive capacity of different sets of linguistic and geographic covariates, we also propose procedures of variable selection.
Recent studies turned to correlate single gene expression with multiple SNPs simultaneously, whereby SNPs were chosen into a final model using sophisticated procedures of variable selection.
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Moreover, bootstrapping technique is employed during the procedure of variable selection and O2-PLS, which can enhance the reliability and robustness of calibration analysis.
Then taking this scaled series as the dependent variable, and following the same procedure of variable selection, we find the following variables as influential - (i) Minimum Temperature, (ii) Maximum Temperature, and, (iii) Maximum Humidity.
We study the impact of selection bias and the usage of permutation tests in the context of variable selection and develop a powerful implementation procedure of variable selection for genome scanning.
For each hierarchical category, we selected predictors (i.e. block of variables) based on a forward step-wise regression procedure of variable blocks using a p < 0.1 significance level [ 79].
The procedure of variable selection, validation and calibration of the final model was performed as described for Model 1. Models 1 and 2 were compared statistically by a likelihood ratio (LR) test.
For the LR model, the stepwise procedure of variable selection again chose seven predictors, four of which (low postoperative cardiac output, postoperative creatinine, age and postoperative bilirubin) were identical to those chosen for the scoring system.
No procedure of variables selection was performed.
A forward selection procedure of variables and their interactions was performed based on the Akaike's information criterion.
Samples were taken prior to biopsies to avoid any confounding effect of the procedure on variables of interest.
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