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In a study that closely mirrored the experimental procedures of the main study presented here, we asked if the results could be driven by a resource trade-off.
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A pilot study of 75 non-smoking women had been conducted before the implementation of the main study to test study procedures and feasibility.
A limitation of the main study will be the inability to follow those clinical conditions that did not have identified ICD-10 or procedure codes.
The hides were tanned and examined after the same procedure as in the main study.
Standard operating procedures were written for all the main study procedures including anthropometric measurements and the oral glucose tolerance test.
The same procedure was performed for the main study, using the two selected concentrations.
For each phase the main study procedures are described below.
The pilot phase aimed to determine participants' acceptability of extensive and repeated phenotyping, the practicality of this procedure and to establish an optimal protocol for the main study.
A total of 118 healthy volunteers entered the main study.
4. The pilot study showed that the procedures, measures, and delivery of the intervention worked well and recruitment began for the main study in October 2006.
All study procedures have been pilot tested and modified as necessary for the main study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com