Conclusions: Results obtained, indicate that the procedures of nanoparticle synthesis, radiolabelling and quality control were reproducible and right to design a biodegradable nanosystem suitable for in vivo theranosis.
Hence, we significantly modified the existing procedures of nanoparticle synthesis in order to obtain palladium nanoparticles of cubic shape (PdC), gold rod-like nanoparticles (AuNR), and nanoparticles with a silver core and a gold shell (AgAu) with a donut-like appearance in TEM (Fig. 1).
In this review, we have attempted to update the procedure of nanoparticle synthesis from algae, their characterization by UV-vis, Fourier transform infrared spectroscopy, transmission electron microscopy, scanning electron microscopy, x-ray diffraction, energy-dispersive x-ray spectroscopy, dynamic light scattering and application in cutting-edge areas.
Atomic force microscopy analysis allowed to optimize the procedure of nanoparticle cluster array fabrication in terms of electron beam dose and chemical protocol, enabling to achieve a good regularity in spacing and size (i.e. area and layer number) of the clusters.
Classical physicochemical synthetic procedures of metal nanoparticles suffer from drawbacks such as polydispersity, low yield [ 1], and use of toxic reagents [ 2].
After the dialysis procedure, the volume of nanoparticle solution was adjusted to 50 ml and then 5 ml of this solution was introduced into a dialysis tube (MWCO = 12,000 g/mol) and then dialysis tube was introduced into a 200-ml bottle with 95 ml of phosphate-buffered saline (PBS, 0.1 M, pH 7.4, 0.1% (w/v) Tween 80).
Scheme 1 Preparation procedure of multifunctional nanoparticles composed of iron oxide nanoparticles and CdTe nanocrystals.
The use of the biopolymer chitosan as a template for the preparation of magnetite and magnetite/silver core/shell nanoparticle systems, following a two-step procedure of magnetite nanoparticles in situ precipitation and subsequent silver ion reduction, is discussed in [36].
A step-wise description of the synthesis procedure of SrFe12O19 nanoparticles is shown in Fig. 1.
Qu and Dai [30] reported a substrate enhanced electroless deposition (SEED) procedure of metal nanoparticles on carbon nanotubes.
The schematic procedure of hybrid nanoparticles includes PEG covering, surface modification, cyclic RGD conjugation, and I-125 labeling.
