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Such enrichment would also apply to sequencing of ChIP samples derived by either cross-linking followed by sonication, or by native ChIP using micrococcal nuclease digestion, as both procedures are unlikely to fragment the genome randomly prior to chromatin immunoprecipitation.
27 28 29 Thus, errors in the coding of caesarean procedures are unlikely to explain the large between trust variation in overall rates of caesarean section.
However, that we identified no significant increase in cases in a population of this size, despite a large decrease in prescribing of antibiotic prophylaxis, suggests that invasive dental procedures are unlikely to account for a high proportion of the cases.
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Finally, sample contamination during RNA extraction and RT-PCR procedures was unlikely because we used a continuous single-sample RNA extraction, and RT-PCR was accompanied by a negative water control.
Despite a significant hypothesis test at the 5% level, the confidence interval also would have shown that the difference between the two surgical procedures was unlikely to be clinically important.
When genes are studied that result in fitness effects sufficiently large to be easily quantified over short time scales, e.g. one growing season, and in experiments with low numbers of replicates, minor molecular changes resulting from the transformation procedure are unlikely to be influential, if the necessary precautions have been followed with transformation procedure.
Thus, issues related to normalization of the BAL procedure are unlikely to explain the observed results.
It worked, though the procedure is unlikely to be adopted by the British Horseracing Authority.
The proposed "statutory instrument" procedure is unlikely to result in adequate parliamentary consideration of such a significant change in child protection and child and family welfare provision.
According to Kagan, even if the new foundation can raise money to continue beyond 2001, the selection procedure is unlikely to become more transparent.
But don't toss out your toupee--the scientists who performed the microtransplant feat, described in tomorrow's Nature, warn that the procedure is unlikely to restore leonine shocks any time soon.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com