The procedure is adjusted as follows. .
The absolute (unsigned) target envelope offset or carrier orientation, depending on the procedure, were adjusted between sequential trials using a 2 down 1 up staircase procedure.
The recruitment procedure is adjusted to each of the centre's internal structures and processes regarding the invitation of patients.
The aqueous and detergent phases from this procedure were adjusted to the equal volume with 10 mM Tris/HCl (pH 7.4) and 150 mM NaCl plus protease inhibitors.
Distraction was carried out 1 week post-operation, and the speed for bone transportation procedures was adjusted to 0.5 mm/day in 4 increments.
After completion of the preparation procedure, the ventilation was adjusted to yield a PaCO2 between 38 and 41 torr (5.0 5.5 kPa).
Given that, for each immunoglobulin, five different comparisons were performed, according to Bonferroni's procedure, alpha value was adjusted to de 0.01 (two tailed) level.
In cases of all-pairwise multiple comparison procedures, the α-level was adjusted by applying a previously described procedure [ 28].
During the experimental procedure, the isoflurane level was adjusted depending on depth of anaesthesia.
