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Programs were written in Perl to generate permutations of the six sequences with observed intron-flanking repeats of length four or greater according to different constraints and to thereby test, by a randomization procedure, the statistical significance of the occurrence of repeats surrounding introns.
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For the unwrapping procedure, the Statistical-Cost, Network-Flow Algorithm for Phase Unwrapping (SNAPHU) package (Chen and Zebker 2002) with the minimum spanning tree method was used.
FZ helped with the experimental procedures, the statistical analyses and the writing of the paper.
Additionally, to account for sample design and weighting in the estimation procedures, the statistical analyses were conducted with weighted data.
The minimum unit to apply these concepts is the MB; this procedure extracts the statistical information from every MB.
We accounted for residual head motion effects by including the motion parameters from the realignment procedure into the statistical model.
We performed all regressions using the PROC REG procedure from the statistical package SAS 9.3.
The Proc Genmod procedure in the statistical package SAS (version 6.12) [ 10] was used.
Data were examined by repeated measurement ANOVA (mixed procedure) of the Statistical Analysis System (SAS Institute Inc. 2003).
Data were analyzed using the analysis of variance procedure in the Statistical Analysis System (SAS) Version 9 (SAS Institute, Cary, NC).
Data were analyzed by using the General Linear Model procedure in the Statistical Analysis System (SAS Institute, version 9.2).
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