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As a first step of our screening procedure, stepwise logistic regression was used to select those anti-GAG antibody types that best discriminated the patient group from the controls.
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They show that MISA also has much better power than standard multiple comparison adjustment methods and false discovery rate procedures, stepwise logistic regression or the lasso.
The information regarding the application of different diagnostic procedures stepwise was not captured in this study.
In relation to the multivariable analysis, automatic procedures (stepwise) were quite common in logistic regression.
In the model-building procedure, a stepwise back ward regression technique was applied.
Several selection procedures (backward, stepwise) were tested in order to check the robustness of the model.
Cox proportional hazards models were estimated by: a) forcing all factors; b) a forward stepwise procedure; and c) a backward stepwise procedure (with p = < 0.05 as selection criterion for stepwise procedures).
The stepwise procedure is illustrated as follows: 1.
To our delight, the stepwise procedure provided a satisfactory result.
We use the stepwise procedure to select the significant variables.
The stepwise procedure is illustrated in Figure 2.
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