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The supplementation procedure in primary fibroblasts consisted of administering 0.5 mM or 2.5 mM 2,4-diHB.
However, there is no adequate evidence supporting the efficacy of such procedure in primary care clinical practice.
Although patients at STI clinics get a full STI screen even if asymptomatic, this is not a routine procedure in primary care.
The major strength of this study is the close fit to the normal procedure in primary care practice and the not invasive character of the case management program.
In conclusion, induced sputum is a safe procedure in primary healthcare settings and can be deployed to improve the quality of sputum for diagnosis or research purposes.
As proof of principle, we performed the identical experimental procedure in primary childhood T-ALL cells isolated from peripheral blood of a 8 year old girl at initial diagnosis.
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However, it is not mandatory to report procedures in primary care, and GPs in Sweden do not normally code procedures [ 5].
The primary care practice maintains comprehensive patient records, which includes information on all contacts and procedures in primary care, hospital, and several other care providers.
In addition, new research could change the emphasis from projects investigating barriers to exploration of fully implemented and integrated procedures in primary and secondary care.
Therefore, in line with routine GP procedures in primary care, study visits are restricted to inclusion on day 0. Further study visits are not mandatory.
KVÅ was chosen for this study because it is used in Swedish health care and has been proposed to be mandatory for reporting procedures in primary care.
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