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General procedure and spectral data of substrates bis-alkoxy methanes (1) and specimen NMR spectra of α-alkoxymethyl phosphonium iodides (2) and vinyl ethers (3) are given in Additional file 1.
Supplementary data General procedure and spectral data.
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Experimental procedures and spectral data for CF3 indomethacin.
Experimental procedures and spectral data for new compounds.
The detailed synthetic procedures and spectral data are available in Supplementary Results (pages 1 40 of Supplementary Information).
Synthetic procedures, chemical and spectral characterization, cell culture and imaging methods, alkaline phosphatase assay details, additional figures as described in the text.
Synthetic procedures, experimental and spectral data for the intermediates and final products evaluated in this study including elemental analyses, high-resolution MS data; H NMR and C NMR spectra for (R)- 7–(R)- 10 and (S) -3.
The Methods section provides the synthetic procedures and physical, spectral, and analytical properties for the final compounds evaluated in the pharmacological studies.
Full synthetic procedures and analytical and spectral characterization data of the synthesized compounds.
Full synthetic procedures and analytical and spectral characterization data of synthesized compounds.
However, direct comparison with other results is challenging owing to differences in the infrared regions used, detector type, and spectral measurement procedure, spectral pre-treatments method, the nature of the samples used, and partly, due to a narrow range of samples in the calibration set.
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