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(Collins 1985, p. 84) Although Collins seems to regard Harrison's problems with replication as casting light on the episode of gravity waves, as support for the experimenters' regress, and as casting doubt on experimental evidence in general, it really doesn't work.
It was suggested that CRMs might be indicative of problems with replication termination, which according to current models takes place in the NCR and may involve the exonuclease activity of Polγ (34).
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This effect could be observed also in other parts of the mitochondrial genome, indicating a general problem with replication fork progression.
In some cases the reduced replicative capacity is due to increased telomere dysfunction (AT), and in others due to problems with DNA replication causing replication stress that lead to high activation of p38 and a high degree of SIPS (ATR-SS and WS).
The problem with replications, then, is that if someone fails to replicate a given study, it might simply be because they didn't have access to this hidden knowledge, and didn't actually run the study in exactly the same way as the original.
For the most part, the problem with replications is one of practicality.
In doing so, we have simultaneously gained insight into the role of processive replication in maintaining transcriptional states and created a sensitive assay that monitors problems with the replication of G4-forming DNA sequences in vivo.
Chang's method however is unable to treat MDVA problems with possible replication of relations.
The basis of the underlying expansion mutation responsible for these disorders is unknown, and problems with DNA replication, recombination and repair have all been suggested as possible mechanisms [ 6].
We defined the query decomposition problem with fragment replication (QDP-FR).
However, the major problem with treating replication in biological contexts is that we do not have an analysis of "information" and related terms up to the job.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com