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Both the total and its two components suffer from problems of variability in definition and analysis, creating challenges when examining intakes and impacts on health.
The perception that not all services are available may reflect problems of variability in treatment availability or it may perhaps reflect some lack of knowledge of the onward services available.
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Let's call this the problem of variability in sense.
To overcome this problem of variability in size and location of the PAC, we employed linear resizing and shearing as well as nonlinear warping of the brain to normalize the individual brains into a standardized stereotactic frame.
We used a similar approach to address the problem of variability in cellular infiltrates in biopsies obtained under US guidance from small joints, and we came to similar conclusions demonstrating that the main component of the variance was due to the differences between patients rather than between samples or cutting levels of the same sample.
Since we use an iterative method to solve the regression problem, interpretation of variability in the ensemble can be further analyzed by looking at the solution trajectory for Lasso (ω vs. Lasso iteration; Figure 5C).
In other words, multicollinearity problems and lack of variability in key factors that necessitate large datasets in many econometric and epidemiological studies do not apply.
Figure 1 defines this problem in terms of variability in care that protocolized care can reduce, and a different, potentially less reducible, component due to inter- and intra-patient variability in response to treatment.
From the clinical experience with purified recombinant IL-1Ra it became clear that most of the problems of variability of efficacy were due to difficulties in adequate timing and dosage of the drug [ 12].
This manifests as a significant problem considering the high degree of variability in the response of patients to rituximab treatment [37], [38], [39], [40].
The problems with defining VISA arise because of variability in the phenotype in the clinical laboratory, variability between phenotyping methods (discussed above), and the large number of rare mutations responsible for altering the sensitivity of the S. aureus cell to vancomycin.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com