Sentence examples for problems of alignment from inspiring English sources
The upgrade to the ISOLDE facility, HIE-ISOLDE, will include an upgrade to the RFQCB (radio frequency quadrupole cooler and buncher), the focus of which will be fixing the problems of alignment with the current machine, improving the integrity of the vacuum system, stabilizing the internal gas pressure, and the changes associated with a new position.
In order to simplify the problems of alignment and reconstruction, we initially imposed sixfold symmetry, which blurs the features of the heptameric ClpP ring.
Nevertheless, we expect that FGB-int7 will be an excellent marker for studying evolution within genera and families where there should be no problems of alignment.
This approach eliminates the problems of alignment due to extensive divergence within the HVRs, and allows identification of closely related HVRs (in different protein variants), thus providing a ready classification of variation generated via point mutation versus recombination in recently divergent proteins.
This fact, coupled with the fact that phosphoserines may shift positions within rapidly evolving disordered regions [ 31] and general problems of alignments of such regions could distort our analysis.
It is designed to overcome the problem of alignment, the flow being aligned with the grid.
Although these conventional studies solve the problem of self-alignment of a part with gripper, the problem of alignment with other part is not considered.
Alignment based methods are difficult to apply at the whole genome level due to the problem of alignment.
The problem of alignment errors arises especially on large-scale phylogenies with many taxa that span a broad divergence range [10], where many homologies lie in the twilight-zone of sequence alignments [11].
Another caveat is that there is a potential problem of alignment reliability especially for noncoding regions.
This is neither a problem a data quality nor a problem of alignment analysis but reflects the fact that the phylogenomics analysis does not accommodate with alignment uncertainty [ 47].
