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We posited that the presence of an unusual degree of purifying selection between a class of human disease genes and their orthologs in a model species may indicate potential problems for studying that particular disease class in that model organism.
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First, we employ artificial benchmark problems: the Weighted LPTNO problem (a generalization of the well-studied LOTZ problem), and the well-studied COCZ problem, for studying the effect of recombination.
A spatially inhomogeneous model problem for studying turbulent nonpremixed reacting flow with reversible reaction is proposed, which admits stationary solutions that are periodic in physical space.
This may be a serious problem for studying the OoL and is worthy of attention.
This is a particular problem for studying speech developmentally, because attention and decision processes develop very slowly [ 5, 6] which may cause us to underestimate children's ability to perceive phonetic contrasts.
This problem demands for studying growth- and longevity phenotypes separately.
Netzer argued for a show that calls them "problems for study".
Current harmonics, voltage harmonics along with voltage flickers are considered as power quality problems for study and analysis.
The literature reflects similar problems for studies which depend on voluntary participation.
Given that breast proliferation occurs relatively late in development, human breast tissue may ultimately be derived from few stem cells, leading to exceptionally large patch size and consequent problems for studies of monoclonality in breast tumours.
Theory provides a road map for studying problems, developing appropriate interventions, and evaluating their successes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com