Rodent models for prostate and ovarian tumors are the most problematic for understanding human disease because of significant interspecies differences in anatomy and tumor prevalence.
This is problematic for understanding the natural history of the disease, identifying the underlying mechanisms, and recruiting patients for clinical trials.
Since direct observation is problematic, the understanding of such pyroclastic density currents (PDCs) represents a challenge whose solution is mainly based on analysis of deposit characteristics.
More problematic for understanding the human health implications of coastal flooding is that these databases mingle estimates of different kinds of losses.
In his attempt to reconcile the eroticisation of lower-class men with ideals of equality and reciprocity, Symonds did not fully realise that class difference, just like age difference, rendered problematic an understanding of consensual same-sex desire.
However, since aberrations in pubertal timing may themselves be related to additional clinical pathology such as the presence of chronic disease or an endocrine disorder, this approach may prove problematic in understanding the normal process of pubertal development.
This seems to conflict with the requirement translation answer above: Why do developers see multiple languages as beneficial for encoding requirements, but problematic for code understanding?
Baron also finds problematic the popular understanding of patriotism which focuses on the country's might and its interests as determined by whatever government is in power.
To summarize our answer to RQ2: MLSD is seen as beneficial for developer motivation and for translating requirements to code, and seen as problematic for program understanding, changes to the system, build management, and developer effort.
The activity was structured into two parts, each addressing different implicit objectives derived from what the instructor had observed as problematic in students' understanding of evolution by natural selection (Table 1): Part I. Objective: to observe the random occurrence of mutations.
Citrus harbors large populations of this insect throughout much of the year in areas where the pest is problematic and improved understanding of the population dynamics and management of H. vitripennis on citrus may be key to its management in the broader agricultural landscape.
