However, ongoing influence on phenotype is problematic to time-invariant IVs such as genetic alleles as all past values of the alter's phenotype post tie-formation must be instrumented (even if they only have an indirect effect on ego's BMI).
From our analysis, it is clear that participants experienced excessive pressure on their time and a problematic relation to time and the forced tempo of life [ 33].
This was in contrast with a study performed in the Emergency Department, where participant recruitment was problematic due to time constraints in conducting the geriatric assessment, and difficulties finding individuals that fulfilled the inclusion criteria [ 7].
It is problematic to measure activation time constants at positive potentials in the presence of rapid inactivation which truncates the activation time course, so this experiment was carried out both in intact (using an envelope of tails protocol) and inactivation-removed S620T channels (using a single-pulse protocol) (Fig. 4A,B).
We also found aspects of timing (duration of morning stiffness, six weeks symptom duration) sometimes problematic to evaluate, as time perceptions are different compared to the Western world.
This communication can be problematic due to time-variant signal fading and the consequent variation in channel parameters.
In the 2.45 GHz band, indoor wireless off-body data communication by a moving person can be problematic due to time-variant signal fading and the consequent variation in channel parameters.
The group has been known to be problematic at times for women of color.
A few participants found the introduction section of the interactive modules somewhat long and "resume" functions to be problematic at times.
Although respondents commended the tool as being useful in clinical practice, many indicated that its utilization had the chance of slowing down patient consultations, which was felt to be problematic at times when patient queues were long.
Stream sediment loads (both bedload and suspended sediment) are problematic to measure due to the time and equipment needed.
