Sentence examples for problematic to study from inspiring English sources

9, 24 Progression across MSK and AAN stages is less well defined, which makes these classification schemes more problematic to study.

The flagellar sheath has proved problematic to study; indeed, to our knowledge, there are no mutations that result in the loss of a sheath in otherwise sheathed flagella.

The fact that these bodies of theory are progressive establishes that cases with reciprocal causation are not inherently problematic to study.

A dilution factor in excess of 15 would be necessary to fully reveal the expected signal shape, however the 1 8 dilution sample already has ~5 μM protein concentration, making larger ratios problematic to study.

The use of ceramic coatings to improve mechanical, chemical, and biological properties of a large variety of materials including polymers and metals has often produced technologically attractive as well as problematic surfaces to study, because of their complicate morphology compared to smooth surfaces obtained, for example, by atomistic processes.

As a consequence, the gene histories for a large majority of their genes are discordant, which means that the traditional tree of life model is very much a problematic framework to study microbial evolution.

One explanation of the dropout in the index group could be that the parents had difficulty understanding Swedish, although they had lived in Sweden for at least twelve years, and thus felt it problematic to take part in a study with such comprehensive instruments as this study used.

Therefore, the primary objectives of this study are to investigate the differences between patients with COPD and resident loved ones' perceptions of patients' health status and problematic ADLs and to study prospectively the effects of a COPD exacerbation on resident loved ones' perceptions of patients' health status and problematic ADLs.

This approach has many advantages over the unsupervised approach that not only traces ancestry to K abstract unmixed populations under the assumption that they evolved independently (Chakravarti 2009; Weiss and Long 2009) but also is problematic when applied to study Jewish ancestry, which can be dated only as far back as 3,000 years (fig. 2).

A single complete, population-based cancer registration system and hence the ability to use cancer incidence rather than cancer mortality data are two of the issues problematic to US studies that our study circumvents.

Interspecies use of microarrays is particularly problematic when using human microarrays to study gene expression in non-human primates that are more divergent to humans than the great apes.