Sentence examples for problematic to estimate from inspiring English sources
Although the THC concentration in OF correlates strongly with that in blood on the population level, it remains problematic to estimate blood THC concentrations based on OF samples for individual drivers (Gjerde et al. [2011b]; Ramaekers et al. [2006]).
It is therefore problematic to estimate the desired sample size.
As argued by Kislyuk et al. [ 17] such extrapolation estimates are likely to be spurious because they depend on the estimation of the occurence of extremely rare genes and genomes, respectively, which are problematic to estimate precisely because they are rare.
However, as snares are difficult to detect and often dispersed widely across large, inaccessible areas it is problematic to reliably estimate their prevalence and no standard survey methods exist.
Such "recycling" of RIMS-samples is not problematic, inasmuch as the samples are used to estimate two independent quantities.
Mapping reads back to more similar sequences to estimate abundances would be problematic because reads could not be uniquely assigned to a particular sequence.
Commenting on these quantitative results is problematic because significantly different approaches have been adopted to estimate informal costs.
The stationarity assumption of extreme events for conducting hydrological frequency analysis to estimate return period and risk is now problematic due to climate change.
Accountants could use a formula to estimate the value of an option, but this is problematic for two reasons.
Pan and core genome size estimates are problematic because they depend on the estimation of the occurrence of rare genes and genomes, respectively, which are difficult to estimate precisely because they are rare.
The main goal of our study was to estimate the spatial distributions of the probability that surface soil magnetic susceptibility exceeds critical levels in a problematic area.
