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Human Rights First legal director Dixon Osburn welcomed the White House's pledge for more transparency but remained "deeply concerned that the administration appears to be institutionalizing a problematic targeted killing policy without public debate on whether the rules are lawful or appropriate".
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Mr. Noriega surrendered after a 10-day standoff with American forces, but he had taken refuge in the Vatican Embassy in Panama, obviously a much more problematic target than the house in Mosul.
Importantly, the functional TRPV1 in keratinocytes could have made them a problematic target seemingly able to generate unwanted side effects and prevent future use of either transdermal capsaicin or RTX.
For such problematic targets, a number of random library-based strategies have been developed that generate large collections of randomly truncated or fragmented constructs and couple these to a screen or selection process to identify rare soluble clones [23] [28] reviewed in [29] [31].
These targets are usually not applicable for in vivo production of monoclonal antibodies in mice; however, highly affine aptamers have been selected against some of these problematic targets [ 5].
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We asked them to review the full ranked list of recommendations from Stage 2, select between five and 10 recommendations that they considered would best meet our aims and highlight any they considered problematic to target.
Research into psychological interventions for substance misuse in BD is at an early stage and no studies have specifically targeted problematic alcohol use.
Moreover, the clinical use of pan-HDAC inhibitors could be problematic as recent targeted gene-deletion studies have provided evidence that individual HDAC isoforms serve very distinct functions within the central nervous system [ 35, 74].
To determine whether cognitive behavior therapy (CBT) targeted to problematic attitudes common among women with functional hypothalamic amenorrhea would restore ovarian function.
One portion of Miller's suit specifically targeted the problematic association of his images with the Jenner name, according to Billboard.
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