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These attributes, however, are assigned to individual reads and do not directly measure the problematic repeats across the genome.
Furthermore, the mapping quality score is limited in that it measures the reliability of the mapped reads only, but does not directly identify the problematic repeats in the genome.
Removal of short sequences (below 170 bp: largely comprising of problematic repeats and sequences predominantly composed of poly-A) resulted in 2858 high quality EST sequences with an average length of 480 bp all available at the ICRISAT Chickpea EST Database [ 38].
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For genome projects that may need to resolve such problematic repeat regions, utilizing assembly statistics such as coverage in combination with either paired-reads, or targeted Sanger sequencing [34], [35] could be useful.
In no way do we want the next generation to repeat the flouting of the Geneva Conventions, nor repeat the abuse of prisoners (whose testimony is problematic), nor repeat the waste of lives and treasury.
VIVIEN SCHWEITZER ORPHEUS CHAMBER ORCHESTRA Carnegie Hall Creating new musical works is not particularly problematic; getting repeat performances of them is.
(3) Although localised sediments evoke developed port infrastructure during the Phoenician and Persian periods, high-resolution reconstruction of the northern harbour's Iron Age history is problematic given repeated dredging practices during the Roman and Byzantine periods.
Reads identified by the GS De Novo Assembler as problematic (Partial, Repeat, Outlier, TooShort) or with High-Quality Discrepancies (HQD) were filtered from the dataset.
This is particularly problematic with repeated gene families like those routinely found for RGHs.
In AKI, metabolites that are normally renally eliminated may be retained [ 37- 42], and accumulation is more likely to be problematic with repeated dosing.
Given the problematic nature of repeated sequences, the best initial alignment was used as a starting point only.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com