The whole publication is problematic, beginning with the accuracy of the designation.
Determining whether statistical results were selectively withheld from the publication was problematic to establish; consequently, reporting bias was coded as 100%% unclear risk.
But some see the collapse of the deal as only a partial loss for Beijing, given that public opposition had made the sale of Mr. Lai's Taiwan publications politically problematic for the island's governing, China-friendly Kuomintang party.
Moreover, comparison of the currently available data for these agents across publications is problematic as the experimental methods, cell lines, and particular conditions employed differ significantly from study to study.
Overcoming, detecting and correcting for publication bias is problematic.
13 14 15 The high doses used in early studies were associated with virilisation, 6 12 14 and even low doses, as reported in a recent Dutch publication, may be problematic.
Formal checks for publication bias were problematic because of the small variation in sample size of the studies, ranging from 142 to 235.
Since it went live 6 months ago, the site "documented over 500 problematic images in over 300 publications".
Since results may be contradictory and studies may differ in more than one aspect, to draw a clear, practical conclusion from the publications may be problematic [ 14].
For observational studies, heterogeneity, lack of detailed reporting, confounding, and bias (in particular publication bias) were particularly problematic.
