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She explained that Jack and Avery having a child was "problematic", observing that it puts a "relatively definite end" to the sexual tension between Liz and Jack that occurred in the show's first season.
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"If evil is somewhat more ineluctable, it also becomes somewhat more problematic," Mr. Morris observes.
There does however need to be evidence that the psychometric characteristics of the PRO instrument are such that there is confidence that changes in scores over time with the application of treatments with some efficacy can be detected [ 10] and that the measurement error (or noise) is not so large that it is problematic to observe meaningful changes in patients' health status.
This study design would have been particularly problematic had we observed differences between the two groups.
Problematic peaks were observed in the high frequency region of the frequency response curve in some of the hearing aids.
Above 12,500 pg total RNA per 25 ?l reaction, we begin to observe problematic qPCR inhibitory phenomena (with Trizol®-isolated tissue total RNA) of Type 1, Type 2, Type 3 (and presumably Type 4) varieties.
Nevertheless, the effective implementation of formative assessment is problematic for an instructor on observing and interpreting the learning evidence in a class period.
Distraction was observed as problematic for both age groups with delayed responses to a lead vehicle-braking event as indicated by delayed accelerator releases.
The activity was structured into two parts, each addressing different implicit objectives derived from what the instructor had observed as problematic in students' understanding of evolution by natural selection (Table 1): Part I. Objective: to observe the random occurrence of mutations.
And Rudolph and Stewart (1998 p. 1076) observed that: "problematic has been the tendency for science educators to use the physics model [that is focussed on laws] in the development of curriculum intended to address general issues concerning the nature of science, thus perpetuating a misunderstanding of scientific method that may foreclose the effective learning of evolutionary biology".
With HIV, unlike tuberculosis, disease duration is life-long, and medications must be given daily, making the routine use of directly observed HAART problematic.
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