He's making the (problematic) observation that the other kid speaks with what he thinks is a "white accent" (intonation, inflection, hard consonants, types of slang, fully pronouncing words with -ing, etc).
This perspective also solves the problematic observation that the human thymus has a much greater complexity of structure than even the aged C57BL/6 thymus, even when assessed at birth, despite having a high functional potential.
This mismatch between scales of investigation and scales of management is problematic because observations of many phenomena depend on the scale at which those observations are made.
Most problematic is the observation that the activity due to tight pterin binding is also retained when the enzyme is incubated overnight with an excess of BH4.
On the basis of field observations, a problematic depositional context was anticipated and this is borne out in the contradictory palynological results which demonstrate evidence for agriculture and abandonment in contemporary horizons and radiocarbon age-depth reversals.
The U.S. EPA coded some observations as problematic or unusual (e.g., "lab issues").
The gaps are problematic because without surface observations, scientists can't adequately validate measurements made from space.
However, a few false positives may not be problematic, since transcriptome-wide observations such as primary component analysis or pathway analysis will not be much affected by a single false positive, since we would be handling hundreds of true changes.
