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However, to say nothing of the severe and highly problematic limitations introduced by sample size, the obvious drawbacks surround precision and accuracy of the measured units so that efforts to improve models and, therefore, theory require, at bottom, efforts to improve the institutional infrastructure needed for such measurement.
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We do not, however, see this as a problematic limitation.
The RW model has one problematic limitation, however: as detailed in the supplementary materials, its equation uses both predictions and prediction errors that are perfectly correlated under mean-correction.
A minority of responses were problematic, and sample limitations call for investigation of habit self-reports among larger and more diverse populations.
Testing for mold asthma relationships is problematic because of limitations of mold methodologies and the lack of biomarkers (Brandt et al. 2006).
Although a recent comparison between drugs to avoid criteria such as Beers and Zhan with expert assessments of problematic prescribing demonstrated the limitations of these criteria to measure prescribing quality, 9 14 15 they have value in making initial prescribing decisions.
The prodrug approach to resolving formulation, delivery, and toxicity limitations on problematic drugs has had its proponents and detractors.
This matrix is so huge that its phylogenetic analysis would be problematic due to memory limitations.
Although interprofessional practice (IPP) offers the potential to enhance rural health services and provide support to rural clinicians, IPP may itself be problematic due to workforce limitations and service fragmentation.
However, in their analysis on PWI, magnetic resonance spectroscopy and amino-acid positron emission tomography Kickingereder et al. concluded that technical limitations were problematic, comparative studies warranted and stereotactic biopsies on structural MRI highly reliable to differentiate between tumor progression and radiation-induced changes [ 21].
Therefore, our cross-national comparison findings may be limited by socioeconomic differences, although the persistence of clinical differences in the analyses that covaried for demographic and illness subtype differences make this potential limitation less problematic.
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