In addition to consent itself, the relation between ethics approval and secondary use was also identified as potentially problematic by interviewees.
Prescribing drugs without adequate indication is problematic, as stated by an interviewee: "Herceptin is supposed to be used only by those patients who are receptor positive.
Interviewees described three problematic aspects of data sharing arising out of this isolation, namely the relation to informed consent and ethics approval; understanding the intentions and values of unknown secondary data users; and understanding the cultural background of sample donors.
Given that most interviews only start to hit their stride at 40 minutes, that could be problematic, but Keys is an unusual interviewee: absolutely obliging and committed to making this brief bit of face-time satisfactory for both parties.
The lack of a consolidated STI policy was considered by interviewees to be very problematic.
Finally, given that younger children may have difficulties in communicating information about internally experienced affective states, the use of an interview based on DSM-IV diagnostic criteria may be particularly problematic, despite the use of parental interviewees [ 39].
However, our problems in individual recruitment suggest that such an approach might have been even more problematic due to selection bias of the interviewees.
One Norwegian interviewee commented, "I know it is problematic and I should be concerned more, but my conscience is not bad because of taking flights at all".
Every interviewee was, or had been, a problematic drug user (currently defined in the UK as a user of opiates and/or crack cocaine [ 12]).
He expected his interviewee, a non-theist, to be morally problematic; his paper was clear on this and I suppose this placed him within the 67percentt mentioned above.
