Sentence examples for problematic in the application of from inspiring English sources

The significant dependence of derived stability constants on measured surface area and choice of site density is well known (e.g. [40, 43]), and may prove to be particularly problematic in the application of surface complexation models to natural sediments, where reactive surface area is difficult to assess [3].

MDRD-6: GFR = 170 × Scr (mg/dL -0.999 mg/dL -0.999x age-0.176 age-0.1760.762 (if female) × serum urea nitrogen-0.170 × albumin0.138 Rationale: As mentioned above, estimation of GFR in cirrhosis is problematic; therefore, the application of the definition of CKD in cirrhosis is challenging.

Mobilization of residual DNAPL in a contaminated aquifer may be problematic for the application of enhanced dissolution remediation techniques such as alcohol or surfactant flushing.

"It's not just the laws that are problematic — it's also the application of laws that operate in favor of the powerful," Ms. Nundy said.

In rural areas, where DAs are very large in size, the application of a tolerance value of 2500 to the ODmatrix was problematic in that it did always not capture the DA centroid.

In this respect both (NB1) and (NB2) are, prima facie, more problematic than (ME1), since the application of expressions is something that is clearly within the voluntary control of S. 38.

As people in these countries consume alcohol in a very detrimental manner, the application of global RRs may be problematic for these countries.

Normalization of instrument is often done in regional centers; as a result the application of these instruments in a nationwide scale can be problematic.

However, the application of a molecular clock is problematic in some cases, because the rate constancy of molecular evolution is a prerequisite [38], [39].

The calculated binding free energies are questionable because of several issues: (i) The variance in the calculated work values is very large (several kT), which makes the application of perturbative methods problematic.

The application of the bistochastic filter in this situation was somewhat problematic.