When businesses' raison d'être is to maximise shareholder value, this becomes problematic for purpose, since making the decisions that are better for society might not necessarily be the most cost-efficient.
Currently available valuation methods, in their entirety, can be costly and time consuming making them problematic for these purposes.
That distinction is extremely problematic for the purposes of establishing Anomalous Monism, and is set aside here in favor of the related (but by no means identical) distinction between strict and ceteris paribus generalizations.
Many researchers merge several years of ACS data to increase sample size, but this is problematic for the purposes of this paper because of my measures of fertility and foreign-born share.
Reynold glyphs are also able to depict negative definite tensors, whereas a quadric surface (ellipsoids representing P → 1 / Q ( v ( P ), v ( P ) ) becomes hyperbolic for negative eigenvalues and problematic for visualization purposes.
Several commercially available tests based on the detection of ACPA have been introduced, but they are problematic for diagnostic purposes, since they are not a prerequisite for the development of RA.
Although this plurality might be seen as problematic for the purposes of replicating and linking specific aspects of the interventions to likely changes in hospital use, in some ways it is the merit of a pragmatic trial.
Of note, residential address was not recorded in the 2009 AEDI data, which is problematic for linkage purposes when there is more than one child with the same name attending the same school.
Although the resulting plurality might be problematic for the purposes of replicating the specific interventions, in some ways it is the merit of a pragmatic trial as it means that our results reflect decisions made by local teams, thus increasing their generalisability to routine clinical practice.
Nonetheless, even there were off-target editing, the edited loci are unlikely to be problematic for our purpose of producing rHSA, as long as they do not interfere with the welfare of these transgenic pigs.
