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To summarize our answer to RQ2: MLSD is seen as beneficial for developer motivation and for translating requirements to code, and seen as problematic for program understanding, changes to the system, build management, and developer effort.
The preference to participate in studies by mail, as opposed to at home with an interviewer or by telephone, is problematic for program managers and researchers because mail surveys tend to have low response rates [ 28].
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Of course, teaching students to survive as writers means teaching them how to publish commercially viable work, which is problematic for programs that define themselves primarily in opposition to "evil commercialism".
LDhelmet is specifically tailored to address issues in Drosophila that may be problematic for programs such as LDhat, like a magnitude fold higher background recombination rate, higher single nucleotide polymorphism (SNP) density, and a large portion of the genome influenced by positive selection (Sella et al. 2009; Sattath et al. 2011).
It is certainly not as potentially problematic for the program as a decision that vouchers violate a standing court order on desegregation, as a federal judge ruled last week in regard to such an order in one Louisiana parish.
Since barcoding efforts focus on identification of species, we hypothesize that such intraspecific polymorphisms will be especially problematic for this research program, if the inversions are not detected and accommodated appropriately in alignments.
Launching over the summer — a traditionally slow time for television — could be seen as problematic for many new programs.
As it is known that long introns can be problematic for gene finding programs [39], it may prove useful for gene finding algorithms to make allowances for the increased length of first introns.
The BALLDock/SLICK developed by Kerzmann is a ligand-specific docking approach for docking carbohydrate or carbohydrate-like compounds, which are often problematic for standard docking programs (56).
Providing medical care in under-served or remote areas is difficult due to limitations of skilled personnel, a lack of equipment, and environmental challenges; these same constraints are problematic for the current space program.
Transitions between coverage status can be particularly problematic for individuals with public program coverage in the United States.
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