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The repetitive and GC rich PE/PPE gene family are known to be problematic for analysis with short read data.
These constraints are problematic for analysis of genomic data because some loci are physically linked, and the number of loci is typically much greater than the number of individuals.
This may have been problematic for analysis as it may not accurately reflect how many times participants practiced different exercises; for example, we found that the course lasted, on average, 6 weeks instead of the expected 4 weeks because people are able to complete the weekly modules in their own time.
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Dynamic features, which model a large execution history, are problematic for WCET analysis.
Since even a single-level cache is problematic for WCET analysis, more levels in the memory architecture are practically not analyzable.
This is problematic for later analysis (each record must be displayed as a single row), and we thus combined the direct and indirect data into a single entry.
Both judged that result to be problematic for ROC analysis, but, as explained above, a dissociation between d' m and pAUC can arise for multiple reasons and is not in any way problematic.
It is important to note that our approach cannot repeat earlier track patterns in a gap; indeed, SSM may artificially create patterns where data are sparse [17], which may be problematic for subsequent analysis.
Our results indicate that CGH data can be problematic for phylogenetic analysis.
Despite the availability of the draft B73 genome sequences, incompleteness and inaccuracy in genome/BAC sequencing or gene annotations remain problematic for eQTL analysis.
The protein sequences of cystatins and stefins are problematic for phylogenetic analysis, because they are quite short, highly divergent and produce low bootstrap values in the phylogenetic trees.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com