In addition, using prediction equations based on serum creatinine concentration can be problematic if creatinine concentrations are not at steady state (Payne, 1986; Perrone et al, 1992).
We note that these cryocooling effects can be especially problematic at ligand concentrations around or below the Kd, which equals the ligand concentration at which half of the protein molecules are bound.
In this work, the effect of epipsammic biofilms developed over riverbed sediments on As retention is evaluated as well as their environmental role in river systems with presence of problematic As (V) concentrations.
During rehearsals, the space is a bit of a nightmare - an unwieldy echo creates a problematic lack of concentration of sound.
This would remove the incentives that make market concentration problematic and maximize competition among mortgage lenders, allowing smaller lenders to access global capital markets without going through privately owned gatekeepers such as Fannie and Freddie.
On the other hand, exclusive expression of MCT2 in the neuronal lactate oxidation complex could be problematic because lactate concentration in cerebral extracellular fluid can rise several-fold (∼3 mM) under physiological levels of neuronal hyperactivation [20], [27] [31].
This standard method is reproducible and in comparison with the original method of [ 13, 16] it is fast, results in very clean samples of larvae, and avoids the problematic sieving for concentration of the minute migrating larvae.
However, performing a high cell density culture (HCDC) is a challenge, mainly because control of both the dissolved oxygen concentration and the flow rate of the feed medium is problematic at high biomass concentrations [ 24, 26].
The results indicated that bioaccumulation causes non-steady state conditions in such ponds, and in extreme circumstances decay events can elevate iodine concentrations to problematic levels.
Coupling HPAEC with mass spectrometry (MS) is problematic as the high concentrations of inorganic bases in the mobile phase can cause blocking of the MS source capillary.
The feeling now is that their neighborhood is being ruined by a high concentration of problematic people".
