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This is especially problematic close to the injection site, and the "high sensitivity" (wider window) setting is therefore most useful for low uptake nodes remote from the injection site.
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The McCain campaign, once merely problematic, is now close to being out-and-out dysfunctional.
"We find it very problematic that, this close to a critical date, there is complete uncertainty as to how the agency will proceed," said Annette L. Nazareth, a partner at the law firm Davis Polk.
Bill Kristol tells us this morning that "The McCain campaign, once merely problematic, is now close to being out-and-out dysfunctional.
Alternative probes were slightly more problematic with closer to 10% outliers and 8% yielding different gene expression conclusions, yet these values are still within a tolerable amount of error for most microarray applications.
Talk story about the problematic close proximity of the private Grace Church School and a private psychiatric clinic for convicted sex offenders, in Greenwich Village.
By James Traub The New Yorker, January 20 , 1997P. 42 Talk story about the problematic close proximity of the private Grace Church School and a private psychiatric clinic for convicted sex offenders, in Greenwich Village.
However, this method is problematic for evaluation points close to boundaries.
This can be problematic for data points close to the margins between bins: small, noisy fluctuations may cause these data points to be improperly assigned to a neighboring bin.
Item 35, 'Has your relationship with your family became closer?', was removed because the wording was problematic (patients who were already close to their family found this difficult to answer) and the time frame was inappropriate (unlikely to be applicable for most people in the last week).
Ship vibrations can become problematic if the exciting frequency is close to a natural frequency of the structure.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com