The presence of null alleles was tested using FreeNA [ 17] i.e. loci with an estimated frequency of null alleles (r) higher than 0.2 were considered as potentially problematic for calculations [ 9].
In 0.1 M H2SO4 solutions, the hydrogen desorption peaks overlap those of Cdad turning the charge calculation problematic.
This deficiency might be problematic for accurate calculation of the activated CCN number concentration on the basis of Köhler theory on the CRM side.
The comparison of the stress state between experiments and simulations is problematic since the calculations based on the measured strain give the stress state on the surface and the simulations in plane strain give the stress state in the bulk material.
In extreme cases, where margins are exceptionally small, we can generate some problematic results with our calculation.
For example, if the average undecided proportion is 7.9percentt, but candidate A is ahead of candidate B by 20 percentage points, the 7.9percentt undecided would not change the outcome of the race even if they all ultimately voted for candidate B. In extreme cases, where margins are exceptionally small, we can generate some problematic results with our calculation.
The use of a spreadsheet to perform the calculation was problematic and could be improved through the use of an approach based on stoichiometric matrices.
However, if scientific research is not able to establish "apparent risks" in a quantitative way, making such a calculation is problematic.
A second issue is sampling variability (problematic for standard error calculations when data are treated as fixed rather than random variables).
Because bird flight mechanics differ vary with size and mass, phylogeny and ecology, selecting a group to model pterosaurs on is problematic and biases flight calculations.
