Despite this growing interest, introducing BPT in the western medical world remains highly problematic as a consequence of four main obstacles.
In addition, this method using CNTs as the test substrate has been reported to be problematic as a consequence of using graphene-based materials (Bitounis et al. 2013; Liao et al. 2011; Seabra et al. 2014).
Although the timing of this group seems problematic as a consequence of a generally higher substitution rate at independent genetic loci see [ 13], a late Cretaceous origin at 100-80 Ma seems realistic based on molecular data [ 13, 45] and a fossil from Burmese amber (Grimaldi, pers. comm).
Critically, we note that sensors with advantageous KM values allow for lower concentrations of sensor to be used in the assays, which makes phosphorylation of the CSox substrate by off-target kinases less problematic and as a consequence increases kinase selectivity in cell and tissue lysate based assays.
A visible abutment-restorative interface is a problematic consequence, especially in the esthetic zone.
We see once again a problematic consequence of interpretations of the argument for mental anomalism (Kim's and now Campbell's) that highlight a strong distinction between normative and descriptive principles.
Many alcoholics, who may have had to cease alcohol consumption due to problems with their alcohol use or physical problems as a consequence of problematic alcohol use, have underlying mental health problems (Guest and Holland, 2011) which may be why we find independent associations of physical health and poor psychosocial health and ex-drinking.
While chronic instability and recurrent injuries are a frequent complication following an initial sprain, the precise reasons why such injuries tend to reoccur are unclear at present, and as a consequence rehabilitation may be problematic.
Two-level supersaturated designs examine more than NSS − 1 factors in NSS experiments, and as a consequence individual factor effect estimation becomes problematic.
Assumptions made about changes to spring flow as a consequence of mine-induced drawdown also appear problematic, with significant implications for the spring-fed wetlands.
