Sentence examples for problem with substantial from inspiring English sources

Mental illness is a public health problem with substantial economic costs.

Deep vein thrombosis (DVT) is a major health problem with substantial mortality and morbidity in medically ill patients.

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver dysfunction and a significant global health problem with substantial rise in prevalence over the last decades.

Injecting opiate use is typically a chronic health problem with substantial adverse health consequences.

Migraine is a common health problem with substantial health and socioeconomic costs.

Community-acquired pneumonia continues to be an acute medical problem, with substantial mortality and morbidity.

I do have a mild case of gynecomastia, some anal seepage, and hip, knee, and bladder problems, with substantial loss of hearing, sight, and sense of smell.

Fracture nonunion, delayed union, and osteomyelitis remain serious problems with substantial morbidity and mortality rates.

This study investigates whether the impact of history of incarceration on ED use is mediated by opiate use and sex trading for drugs or money, two current public health problems with substantial risks to individual health.

Alcohol use disorders affect approximately 4 5% of the world population [1], [2] and impose major public health and social problems with substantial worldwide economic loss [3].

In the last decades, ambient pollutants, combustion generated particles and polycyclic aromatic hydrocarbons associated with them have been identified as health problems with substantial impact on our immune responses [3] [5].