She said the problem was "reaching dangerously high levels" in all parts of the world and could lead to "the end of modern medicine as we know it".
The solution of the problem is reached as the limit of a sequence whose elements are obtained from the minimization of a functional.
Some policy analysts are hopeful that the problem is reaching critical mass.
With state revenues in free fall, the problem is reaching crisis proportions.
This month, the Care Quality Commission suggested this problem is reaching a tipping point [pdf].
Mr. Edwards's biggest problem is reaching enough voters quickly enough.
For Edward Serotta, as for many other people, the problem is reaching that state of flow to begin with.
With state revenues in free fall, the problem is reaching crisis proportions and creating a legal and moral challenge for the criminal justice system, state legislatures and the legal profession.
His problem is reaching out to swing voters at a time when the number of self-identified Republicans is up to ten points lower than the number of self-identified Democrats.
The problem is reaching near-crisis proportions while President Park Geun-Hye calls for "a second miracle on the Han River" – the broad, twisting waterway that bisects Seoul.
