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Fourthly, although CPRD prevalence rates and trends generally agree with nationally reported rates (table 3), some small differences exist that might indicate with election bias or a problem representativeness.
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Then we started to work with the other samples (Sect. 2) and also found a problem of representativeness.
Another way to address the problem of representativeness of online job vacancy data as an accurate sample of job vacancy data is to employ statistical tools that account for sample design problems.
One general problem is representativeness of administrative data.
Paradoxically, large RCTs and "megatrials" (sometimes including more than 10,000 patients) [ 16] with heterogeneous samples have not solved the problem of representativeness [ 17]; indeed, they have aggravated it.
While acknowledging the problem of representativeness of our panellists, we feel that this Delphi survey provides us with important insight into the views of this group of PI experts.
This is quite surprising since study results are rather diverse and sometimes even contradictory: often due to problems of representativeness as well as temporal and/or geographical differences of the respective data.
The number of studies is limited and may lead to problems about representativeness of the large drug user population in China.
Also contributing to the low rate of IgG seropositivity could be that the test has a lower sensitivity in a consecutive stream of routine patients compared to studies on selected well defined cases, as these studies may have inherent problems with representativeness[ 5].
However, problematic incentives for participation in the calculation can bias the calculated costs; the G-DRG tariff calculation has a representativeness problem.
However, the low response rate was not considered a major problem regarding the representativeness of the results, because at least one survey form was returned from each workplace.
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