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Furthermore, the deposition of these data in accessible public databases can help to address the problem of publication bias commonly seen in candidate gene association studies.
The ongoing problem of publication bias shows that unbiased decision making in health care requires mandatory public disclosure of all clinical trial data.
For years, researchers have talked about the problem of publication bias, or selectively publishing results of trials.
How do scientists in the field of genetic epidemiology see the problem of publication bias, what are the possible solutions and what particular pressures are they under that might either promote or prevent publication and other biases?
The problem of publication bias was well understood more than 40 years ago.
The public availability of databases from genome-wide association studies provides an excellent setting where the problem of publication bias can be minimized or even extinguished [8], [9].
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These reviews addressed aspects such as existing terminology to describe problems of publication and related biases, 5 available methods to detect and measure dissemination bias, 12 and the extent, 13 and impact, 14 of the problem of non-publication of research findings.
A key example of this is that trial registration is already helping to address the pertinent problems of publication bias and selective reporting bias by allowing reviewers to find non-published trials and non-published outcomes when conducting systematic reviews.
Dubben et al [38] looked at whether study publication bias exists in studies which investigate the problem of study publication bias.
Philip Hensher writes for the Guardian: "I don't think I've ever heard so many novelists say, as over the last two or three days, 'Well, we might as well just give up, then.' " The inclusion of all English language writers has been talked about for years but has been resisted, partly because of the problem of different publication dates in the US and UK.
Indeed, so rampant and potentially serious has the problem of internet publication become that the criminal law is now coming to the fore as being the most potentially effective means of controlling, albeit to a limited extent, the more dangerous and harmful online abuse.
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