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Nevertheless, the magnitude of this problem mandates the need for novel therapeutic agents.
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"Our problem with mandates is that this stuff is not free," said Joe Luchok, spokesman for the Health Insurance Association of America.
IF there is a problem with mandates, why do they seem to work in countries like Switzerland and the Netherlands?
Therefore, HCV continues to represent a significant public health problem that mandates intensified efforts and investment in both clinical management and research.
We need funders and regulators to take ownership of this problem and mandate gold-standard working practices to eliminate it.
California acted on the problem this year, mandating that hospitals aim at an overall ratio of no more than five patients a nurse in wards like Mr. M.'s.
Although the city tried to combat the problem by mandating stormwater controls for all new development in 1997, it has done little to fix runoff problems caused by buildings constructed before that time.
(This helps explain, at least in part, why such a large percentage of randomized clinical trials cannot be replicated. (ClinicalTrials.gov has tried to fix this problem by mandating the public registration of every clinical trial in advance).
A further problem is "mandate creep," which we've seen at the state level, as groups lobby for various types of coverage — whether for acupuncture, alcoholism and fertility treatments, for example, or for chiropractor services or marriage counseling.
Setting aside these problems, NHST mandates a simplified approach to empirical research that assumes binary increments to knowledge and often produces results of limited theoretical substance.
Montana is one of a handful of states that have tried to solve the problem by mandating that any such fees go to workers.
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