Sentence examples for problem is substantial from inspiring English sources

So, the gender problem is substantial and endemic and getting worse.

"The problem is substantial, and the chasm of ignorance is huge".

The computational cost of optimization method in the optimal well placement problem is substantial.

This problem is substantial, affecting 1.89% of all United States' energy use.

The magnitude of such a problem is substantial if one considers that in yeast alone there are ∼6000 genes potentially regulated by up to ∼400 proteins, thereby producing ∼6000×2400 possible bound/unbound states.

The economic impact of this problem is substantial because it affects the majority of children at some point in their lives and often necessitates doctor visits.

The public health burden of childhood mental and behavioural problems is substantial.

Results: Among 41 (25%) questionnaires categorized independently by 2 investigators, strength of agreement in categorizing 68 pain problems was substantial (κ=.68).

The differences in lengths of stay between hospitals that do not have problems in transferring these patients to long-term care facilities and hospitals that do have these problems are substantial.

19 21 If the increases in healthcare costs between those with and without sleep problems are substantial, these excess costs would provide a strong driver for implementing more systematic prevention and treatment.

The data for the [Ti] experiments present the problem that there is substantial overlap of bands associated with [Si] with those that appear in the [Ti] experiments in the wavenumber region 3650 3450 cm−1.