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This is a problem for the detection of bacterial DNA when two specific conditions apply: 1) Target DNA is present in very small quantities; and 2) Bacterial species are unknown, possibly mixed, and the assay cannot be designed to exclude specific species.
It is evident from our data, therefore, that sulfate minerals represent a potential problem for the detection of organic matter on Mars by thermal extraction methods.
In patient sample, the high abundant proteins like albumin and immunoglobulin create problem for the detection of less abundant proteins through high throughput techniques like mass spectrometry.
The latter being a special problem for the detection of N-terminal signals because of the wrong predictions of gene starts common when using gene prediction software.
However, provided that the extent of misclassification of exposure does not vary by genotype, differential misclassification between cases and controls may not be a serious problem for the detection of departures from a multiplicative G - E joint effect [ 9].
This issue of multiple probe sets for the same gene does become a problem for the detection of the smallest gene sets in the case in which the partitioning pattern is realized exclusively in probe sets all of which spot the same gene.
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However, it still has several defects, for example, premature convergence, stagnation phenomenon, and slow convergence speed in the later evolution period, which imply that the PSO should be further improved, especially for a specific complex problem, for example, the detection of SNP-SNP interactions.
This is a major problem particularly for the detection of blood-based biomarkers as the expected differences are small.
Because of the restricted bowel regime and the presence of tagged stool, a primary 2D axial evaluation (primary window setting 1500, −250 HU) was carried out with 3D problem solving for the detection of polyps.
A common problem in applying biosensors for the detection of genomic DNA is detecting short sequences in large amounts of long double stranded DNA.
Another recent work [31] has seen the use of 'conversation-based' approach in the P2P domain, but for a different problem, namely, the detection of overlapping P2P communities in Internet backbone.
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