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This high-throughput IS-seq method, which can also be used to map insertions in other organisms, extends previous surveys of in vivo interrupted loci and provides a baseline for probing the consequences of disruptions in M. tuberculosis strains.
By probing the consequences of tRNA anticodon modification loss for translation in vivo, we show that codon-anticodon interactions are an evolutionarily conserved modulator of decoding speed in eukaryotes.
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Social issues set his own mental juices flowing, and his best films not only probed the consequences of prejudice, corruption and betrayal, but also celebrated individual acts of courage.
We probed the consequences of nonheptad inserts using a designed leucine-zipper system.
Finally, the model we constructed allowed us to probe the consequences of mutation on evolution.
2) The authors probe the consequences of altered stimulus number.
The mutant proteins allowed us to probe the consequences of dimer interface destabilization without additional complicating factors that arise when comparing experiments performed at differing pH.
Thus, it is still far from thoroughly verifying the effectiveness of TCM in neurological diseases treatment, and it shows that we can probe the consequences of TCM quantitatively with a target specific imaging technique.
In probing the consequences and possible causes of his phobias, Mr. Shawn has written a brave, eccentric and utterly compelling book that's as revelatory and candid as anything ever written by Joan Didion, and as humane and scientifically fascinating as any one of Oliver Sacks's case studies.
By probing the transcriptional consequences of anchorage independence of eight independent mILC cell lines, we identified candidate Kaiso target genes as judged by the presence of the consensus KBS site in their promoter regions.
Although unsuitable for clinical development, this compound has proved to be extremely useful for probing the cellular consequences of Ras pathway inhibition.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com