Sentence examples for probes of function from inspiring English sources

RNA is an extremely important target for the development of chemical probes of function or small molecule therapeutics.

Oligonucleotides, however, have several suboptimal properties as therapeutic modalities or chemical genetics probes of function, including poor cellular permeability and nonspecific stimulation of the immune system.

Finally, we hope we have offered encouraging preliminary rationale for further systematic study of customized music cognition tests as probes of function in dementia syndromes.

Powerful genetic tools enabling the probing of functions of both coding and non-coding genome sequences are urgently needed to facilitate the progress in determining the genetic factors that contribute to our uniqueness as human beings in a post-genomic era.

This course will introduce students to various methods and approaches used in this field, with an emphasis on the use of natural products and synthetic small molecules as probes of biological function.

These autoantibodies will be useful probes of the function of dsRNA-binding proteins.

Peptides from the binding sites of these proteins serve as valuable probes of protein function.

Contrast agents for magnetic resonance imaging (MRI) have recently been used as cellular-level probes of neural function.

There is strong interest in developing small molecules that modulate protein-protein interactions (PPI), since such compounds could serve as drug leads or as probes of protein function.

In addition to their therapeutic potential, these antibodies may find utility as biomarker tools, for detection of Notch1 on the surface of tumor cells, and as probes of Notch1 function and signaling mechanisms.

Further, small molecules can be dosed to achieve varying levels of target inhibition and as such can be elegant probes of protein function.