Sentence examples for probe the specificity of from inspiring English sources

An approach has been developed to use N-glycans to probe the specificity of animal lectins in vivo.

So as to probe the specificity of the cRGD and cRAD constructs in the parent OVCAR5 line, a 3D in vitro spheroid model was employed that replicates many of the features found in vivo, in particular the presence of extracellular matrix9,19,31,32.

This article describes the use of a novel domain (the GoLoco motif) found in several members of the regulators of G-protein signaling (RGS) protein family to probe the specificity of Gα subunit involvement in the coupling of dopamine and somatostatin receptors to ion channels in the AtT20 neuroendocrine cell line.

We used a cell culture assay to express receptors and probe the specificity of ligand-receptor interaction [18].

In addition, we undertook competition experiments with an excess of unlabelled oligonucleotides and included a version with a mutant ZRE to further probe the specificity of the interaction.

To probe the specificity of BSA action, we determined the effect of alcohol dehydrogenase, deoxyribonuclease, ribonuclease, lysozyme, ovalbumin, cytochrome c and hexokinase at a concentration of 19 µg/ml on the reactivation of TbTIM and stability of the dimer.

To understand the relationship between TCR/pMHC affinity and cross-reactivity, we sought to engineer an additional weak interaction, termed "velcro," between the TCR and pMHC to probe the specificities of TCRs at relatively low and high affinities.

Other investigators, using non-invasive recording methods, have probed the specificity of response changes by altering the acoustic properties of the feedback stimulus and examining how brain responses are affected by induced mismatches between the intended vocalization and the speech signal heard by the subject [9], [49], [53].

In general, this method is a highly efficient strategy for rapidly probing the specificity of this important enzyme.

In general, this is a highly efficient strategy for rapidly probing the specificity of this important enzyme and should be useful for a variety of future studies on PFTase and related enzymes.

We also probed the specificity of the hydrolase-PKS interactions by incubating Bref-PKS with CazE from the chaetoviridin pathway and Fma-AT from the fumagillin pathway, both known to participate in release of reduced polyketide products from the respective HPPKS partners.